Technical services
Carcinogenicity experiment
Carcinogenicity experiment
Carcinogenicity testing is conducted to evaluate the potential carcinogenic effects of a drug in animals, thereby assessing and predicting its possible hazards to humans. Any concerns arising from experimental studies, animal toxicity tests, or data from human applications may indicate the need for carcinogenicity testing. Drugs expected to be used by patients over a long period should undergo carcinogenicity testing in rodent species. We were among the first in China to conduct carcinogenicity studies under GLP-compliant conditions and have established a comprehensive carcinogenicity evaluation system. The study designs fully comply with the guidelines of the FDA, ICH, and CFDA and adhere to international GLP standards.
We have a team of Japanese veterinary pathologists (JCVP) and toxicopathologists (JSTP) with nearly 30 years of experience in carcinogenicity testing and diagnosis, boasting extensive expertise in this field. Our pathology team is among the best in China, featuring high-level specialists. We offer comprehensive and sophisticated diagnostic support using tumor markers. Through years of practical experience, we have accumulated rich expertise and historical control data, and have established a database of spontaneous lesions in experimental animals, including an image library of spontaneously occurring tumors.
| Test Type | Types of Tumor Marker-Assisted Diagnosis |
2-Year Carcinogenicity Study in Rats Carcinogenicity Study in Mice Aged 18-24 Months 6-Month Carcinogenicity Study in rasH2 Transgenic Mice Carcinogenicity Study in 6-Month-Old P53-Deficient Mice Tumor/Carcinogenicity Study in Immunodeficient Mice (Cell Therapy Products) | Epithelial cell origin: Cytokeratin Neural tissue markers: S-100, GFAP, Neurofilament Myofiber source: Smooth muscle actin Source of neuroendocrine tissue: Chromogranin A Fibrous connective tissue origin: Vimentin |
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Ms. Li:+86 15760970681
Mr. Su:+86 19991001701
Landline:+86-29-33656828
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4th Floor, Unit C. Building 9. Small and Medium-sized
Enterprise Park, Airport Industrial Zone Airport New Ciy,Xixian New Area, Shaanxi Province
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WhatsApp：8613940397353
Email：hr-xian@grglp.com
Landline：862933656828
Mr. Su：8619991001701
Ms. Li：8615760970681