Technical services
Formulation Safety
Formulation Safety
Formulation Safety
The safety tests for pharmaceutical formulations primarily include irritation, sensitization, and Hemolysis tests. These tests evaluate the toxicity—such as local irritation and local allergic reactions—that may occur at the site of administration when a drug formulation is administered via non-oral routes, including through the skin, mucous membranes, body cavities, and blood vessels, as well as any systemic toxicity—such as systemic allergic reactions and hemolysis—that may arise from systemic exposure. These tests are an integral part of preclinical safety evaluation.
Irritation test
Vascular Irritation Test
Muscle Irritation Test
Skin Irritation Test
Mucosal Irritation Tests: Ocular Irritation Test, Irritation Test for Nasal Drops and Inhalants, Vaginal Irritation Test, Rectal Irritation Test, Oral Medication Irritation Test, Ear Drop Irritation Test
Allergy testing (guinea pigs, rats, mice):
Active Systemic Anaphylaxis Test
Passive Cutaneous Anaphylaxis Test
Active Cutaneous Anaphylaxis Test
Guinea Pig Buehler Test
Guinea Pig Maximization Test
Skin Photoallergenicity Test
Hemolysis test:
In Vitro Hemolysis Test
In Vivo Hemolysis Test (Animal Model)
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