Technical services
Toxicological Evaluation of Pesticide Registration Trials
Pesticides are chemical agents used in agriculture to control pests and diseases, as well as to regulate plant growth. They are widely applied in agricultural, forestry, and animal husbandry production, environmental and household pest control and disease prevention, and the prevention of mold and insect damage in industrial products. There are many types of pesticides; classified by use, they can be mainly divided into insecticides, acaricides, rodenticides, nematicides, molluscicides, fungicides, herbicides, and plant growth regulators. Classified by their source materials, they can be divided into mineral-origin pesticides (inorganic pesticides), bio-origin pesticides (natural organic substances, microorganisms, antibiotics, etc.), and chemically synthesized pesticides. By chemical structure, they mainly include organochlorines, organophosphates, organonitrogens, organosulfurs, carbamates, pyrethroids, amide compounds, urea compounds, ether compounds, phenol compounds, phenoxy carboxylic acids, amidines, triazoles, heterocyclic compounds, benzoic acid compounds, and organometallic compounds—all of which are synthetically produced pesticides. According to their formulation type, they can be categorized into powders, wettable powders, emulsions, emulsifiable concentrates, creams, pastes, colloidal formulations, fumigants, fumigating agents, smoke agents, granules, microgranules, and oil formulations, among others.
Toxicological Evaluation of Pesticide Registration Trials
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Serial number
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Testing items
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Acute toxicity
Experiment |
1
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Acute Oral Toxicity Study in Rats
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2
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Acute Dermal Toxicity Test in Rats
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3
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Acute Eye Irritation/Corrosion Test in Rabbits
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4
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Acute Skin Irritation/Corrosion Test in Rabbits
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5
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Guinea Pig Skin Sensitization Test
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6
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Acute Inhalation Toxicity Study in Rats
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Repeated exposure
Toxicity test |
7
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28-Day Repeated Dermal Toxicity Study in Rats
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8
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28-Day Inhalation Toxicity Study in Rats Following Repeated Exposure
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9
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Subchronic (90-day) Oral Toxicity Study in Rats
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Special toxicity
Experiment |
10
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Reproductive Toxicity Study in Rabbits During Pregnancy
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11
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Rat Prenatal Developmental Toxicity Study
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12
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Two-Generation Reproductive Toxicity Study in Rats
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13
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Mouse bone marrow erythrocyte micronucleus assay
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14
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In Vitro Mammalian Cell Gene Mutation Assay
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15
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In vitro mammalian cell chromosome aberration assay
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16
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Bacterial Reverse Mutation Assay
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17
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Analytical Method Validation
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18
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Mouse carcinogenicity test
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19
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Chronic and Carcinogenic Combined Studies in Mice
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20
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Mouse Neurotoxicity Test
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21
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Acute Delayed Neurotoxicity Test in Chickens
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Metabolic toxin
Kinetic test |
22
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Toxicokinetic study
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Test Scope
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Acute Toxicity Test
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Repetitive Dose Toxicity Study
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Metabolic Toxicokinetics Study
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Poison
reason study Try Test |
Acute Oral Toxicity Test
Acute Dermal Toxicity Test Acute Inhalation Toxicity Test Eye irritation test Skin Irritation Test Skin Sensitization Test |
Subchronic (or Acute) Oral Toxicity Study
Subchronic (Acute) Dermal Toxicity Test Subchronic (or Acute) Inhalation Toxicity Study Chronic toxicity test |
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