General Toxicological Safety Assessment
Our company’s core team boasts extensive experience in toxicology research and has conducted hundreds of drug projects as well as thousands of general toxicology studies for pesticides on behalf of our sponsor. Our product portfolio encompasses chemical pharmaceuticals, biotechnology products, traditional Chinese herbal medicines, and chemicals of various kinds. We are able to provide sponsor with sound study designs and appropriate dose selections, ensuring the smooth execution of toxicology studies. Our general toxicology studies comply with international GLP regulatory standards and can be tailored to meet the regulatory requirements of different countries, thereby satisfying sponsor’ needs for clinical trial applications or market authorization.
Type of experiment
| 1. Dose Range Determination Study | Clearly define the safe dosage range of the drug to lay the foundation for subsequent trials. |
| 2. Single-Dose Toxicity Study | Assess the acute toxicity response following a single dose of the drug; |
| 3. Repeated-dose toxicity studies accompanied by toxicokinetics | Supports 1-, 3-, 6-, and 12-month cycles, enabling the analysis of toxicity profiles and toxicokinetic patterns associated with long-term administration. |
| 4. Local Toxicity Test | Evaluate the irritation and toxic reactions of the drug at the local administration site. |
| 5. Immunogenicity Test | Verify whether the drug triggers immune-related adverse reactions; |
| 6. Safety pharmacology studies | Assess the effects of the drug on the body's major physiological systems. |
Experimental route of administration
Covering multiple administration routes including oral (gavage, capsules), topical (skin and mucous membranes), intravenous (bolus injection/continuous infusion), subcutaneous, intradermal, intramuscular injection, ocular, and respiratory;
Types of test substances
Supports the evaluation of a wide range of study materials, including chemical drugs, biological products, traditional Chinese medicines, and natural medicines.
Test animal species
We offer a variety of experimental animal options, including rodents and non-rodent species.
More fields
As an institution in Shaanxi Province that has obtained NMPA drug GLP certification and completed its qualification re-examination and scope expansion in 2024, Guorui Yinuo has built a “global + domestic” dual-compliance service capability in the pharmaceutical sector.
The one-stop service platform for veterinary drugs—GLP/GCP—is a specialized service provider that offers an integrated solution—from non-clinical evaluation to clinical trials and registration submission—aligned with both the Ministry of Agriculture and Rural Affairs’ GLP/GCP standards for veterinary drugs and the international OECD GLP standards, covering the entire R&D process for veterinary pharmaceuticals. At its core, this platform addresses the key pain points faced by companies, including long R&D cycles, high compliance barriers, and fragmented resources.
As the only organization in the Northwest region to have obtained OECD GLP certification in the pesticide field, Guorui Yinuo passed the international assessment with a zero-defect record. Relying on its compliance credentials, comprehensive technological capabilities across the entire value chain, and high-standard laboratory platform, Guorui Yinuo provides integrated solutions for global pesticide companies—from research and development all the way through registration.
Relying on the OECD GLP zero-defect certification qualification, chemical test data can be globally recognized and simultaneously comply with both domestic and international chemical regulatory requirements as well as relevant requirements of the Ministry of Ecology and Environment, efficiently supporting needs such as chemical registration and export declarations.
Shaanxi Guorui Xinchuang Medical Technology Co., Ltd. is an independent, third-party clinical preclinical safety evaluation research institution for medical devices. It was registered and established in June 2020 in the Airport New City and is currently the most comprehensive medical device safety evaluation institution in Northwest China. The company primarily provides product safety evaluation services to R&D enterprises specializing in Class II and Class III medical devices.
A full-process technology empowerment platform from target discovery to IND submission
Early Toxicity Prediction and Screening
Early toxicity screening is an essential and indispensable step in the new drug development process. Early termination of compounds that show no development potential can save sponsor substantial amounts of manpower, resources, and time. We offer sponsor comprehensive early toxicity screening services, including early genotoxicity assessment, early general toxicity assessment, and early reproductive and developmental toxicity assessment.
We are equipped with specialized instruments and devices, including flow cytometers, microplate readers, fluorescence microscopes, and PCR machines. These resources enable us to establish animal models for diseases affecting the tumor, cardiovascular, respiratory, metabolic, and urinary systems, and to conduct comprehensive and systematic preclinical studies on drug efficacy and mechanisms at multiple levels.
Contact phone number
Ms. Li:+86 15760970681
Mr. Su:+86 19991001701
Landline:+86-29-33656828
Company Address
4th Floor, Unit C. Building 9. Small and Medium-sized
Enterprise Park, Airport Industrial Zone Airport New Ciy,Xixian New Area, Shaanxi Province
©2026 Xixian New Area Guorui Yinuo Drug Safety Evaluation and Research Co., Ltd.
WhatsApp：8613940397353
Email：hr-xian@grglp.com
Landline：862933656828
Mr. Su：8619991001701
Ms. Li：8615760970681